Studies on the Complex Molecular Etiology and Cellular Landscape of Hip Osteoarthritis
Status: Recruiting
Location: See all (4) locations...
Intervention Type: Procedure
Study Type: Observational
SUMMARY
The purpose of this study is to cast light on the highly complex etiology and cellular landscape of hip osteoarthritis by utilising single-cell and spatial omics.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 74
Healthy Volunteers: t
View:
• Cases: Adult patients with osteoarthritis in the hip joint and who are going through an elective total hip arthroplasty.
• Controls: Non-arthritis adult patients who are going through a trauma-based emergency total hip arthroplasty.
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• Adult patients with rheumatoid arthritis in the hip joint and who are going through an elective total hip arthroplasty.
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Locations
Other Locations
Finland
Helsinki University Hospital
RECRUITING
Espoo
PET-centre, University of Turku
ACTIVE_NOT_RECRUITING
Turku
Turku Bioscience, University of Turku
ACTIVE_NOT_RECRUITING
Turku
Turku University Hospital
RECRUITING
Turku
Contact Information
Primary
Lea Mikkola, PhD
limikk@utu.fi
+358404143300
Time Frame
Start Date: 2023-01-11
Estimated Completion Date: 2028-12
Participants
Target number of participants: 110
Treatments
OA cases
Fifty adult patients who have hip osteoarthritis.
RA cases
Forty adult patients who have rheumatoid arthritis in the hip joint.
Non-arthritic controls
Twenty adult patients who go through trauma-based emergency total hip arthroplasty and do not have arthritis.
Related Therapeutic Areas
Sponsors
Collaborators: Hospital District of Helsinki and Uusimaa, Turku University Hospital
Leads: University of Turku